Hypersensitivity transfusion reactions due to IgA deficiency are rare according to French hemovigilance data
نویسندگان
چکیده
منابع مشابه
IgA deficiency: implications for transfusion.
Anaphylactic transfusion reactions are acute, potentially life-threatening events with generalized signs and symptoms. Usually IgE mediated they may also result from antigen -antibody reaction involving non-IgE antibodies which fix complement and generate anaphylatoxins. The best documented reactions of the latter type result from presence of anti IgA antibodies in IgA deficient patients who re...
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Hemovigilance is used to track and reduce the occurrence of adverse events associated with blood donations (1). Hemovigilance programs have now been in existence for about 20 years after being developed in 1993 in France. Although it has emerged as a tool to improve transfusion safety, many countries and centers are still in the development stage and have not yet established functioning hemovig...
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Plasma incompatibility was investigated as a possible factor in transfusion reactions in dogs. Urticaria, failure to retain within the circulation the equivalent of transfused plasma volume and protein, and increased gastric acid secretion almost invariably followed transfusion of plasma from another dog but not transfusion of the dog's own plasma. The cutaneous reactions were abolished and the...
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BACKGROUND Hypersensitivity reactions to metronidazole are infrequently described. However, we believe that such reactions are increasing due to growing use of the drug for the treatment of amebiasis and anaerobe infections combined with other antibiotics. The present study assesses the need for oral provocation in patients with probable hypersensitivity reactions to metronidazole. METHODS We...
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Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2017
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2017.03.029